MEFISTO models

MEFISTO is a method for the functional integration of spatial and temporal omics data. More information can be found on the method’s website.

These tutorials adapt the original MEFISTO tutorials to use muon for training:

• application to an evodevo gene expression atlas: gene expression data from 5 species and 5 organs across development;

• application to a longitudinal microbiome dataset: microbiome data from 43 children over the first two years of life;

• application to spatial transcritptomics data: spatial transcriptome data of a mouse brain tissue generated using 10X Visium.