MEFISTO models
==============

MEFISTO is a method for the functional integration of spatial and temporal omics data. More information can be found `on the method's website <https://biofam.github.io/MOFA2/MEFISTO)>`_.

These tutorials adapt `the original MEFISTO tutorials <https://github.com/bioFAM/MEFISTO_tutorials>`_ to use `muon` for training:

- `application to an evodevo gene expression atlas <1-MEFISTO-evodevo.html>`_: gene expression data from 5 species and 5 organs across development;

- `application to a longitudinal microbiome dataset <2-MEFISTO-microbiome.html>`_: microbiome data from 43 children over the first two years of life;

- `application to spatial transcritptomics data <3-MEFISTO-ST.html>`_: spatial transcriptome data of a mouse brain tissue generated using 10X Visium.


.. toctree::
   :hidden:
   :maxdepth: 3

   1-MEFISTO-evodevo
   2-MEFISTO-microbiome
   3-MEFISTO-ST